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shRNA set against Mouse ITSN1 (NM_010587.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH321745

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Gene Information

Cat. No. SHH321745
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr ITSN1
Gene Name Itsn1 intersectin 1 (SH3 domain protein 1A) [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Itsn1 intersectin 1 (SH3 domain protein 1A) [ Mus musculus ]
Gene Symbol Itsn1
Synonyms Ese1; Itsn; Ehsh1; Sh3p17; AA517634; AA545208; AI316805; AI839402; AI848451
Gene Description intersectin 1 (SH3 domain protein 1A)
GeneID 16443
Uni ProtID Q8C4B5
mRNA Refseq NM_010587.2
Protein Refseq NP_034717.2
Chromosome Location 16 C3.3-C4; 16
Function Rho guanyl-nucleotide exchange factor activity; calcium ion binding; guanyl-nucleotide exchange factor activity; kinase activator activity; phospholipid binding; proline-rich region binding; protein binding; protein complex scaffold;
Pathway Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; NRAGE signals death through JNK, organism-specific biosystem; Rho GTPase cycle, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by GPCR, organism-specific biosystem;
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