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shRNA set against Mouse IKBKE (NM_019777.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH318017

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Gene Information

Cat. No. SHH318017
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr IKBKE
Gene Name Ikbke inhibitor of kappaB kinase epsilon [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Ikbke inhibitor of kappaB kinase epsilon [ Mus musculus ]
Gene Symbol Ikbke
Synonyms Ikki; IKK-i; AW558201; IKKepsilon
Gene Description inhibitor of kappaB kinase epsilon
GeneID 56489
Uni ProtID Q9R0T8
mRNA Refseq NM_019777.3
Protein Refseq NP_062751.2
Chromosome Location 1 E4; 1
Function ATP binding; IkappaB kinase activity; NF-kappaB-inducing kinase activity; kinase activity; nucleotide binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups;
Pathway Activated TLR4 signalling, organism-specific biosystem; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, organism-specific biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Hepatitis B, organism-specific biosystem; Hepatitis C, organism-specific biosystem; Hepatitis C, conserved biosystem;
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