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shRNA set against Mouse Hmga1-rs1 (NM_001166476.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH313273

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Gene Information

Cat. No. SHH313273
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr Hmga1-rs1
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Target Gene Hmga1-rs1
Background Predicted to enable several functions, including catalytic activity, acting on DNA; nuclear receptor coactivator activity; and nucleic acid binding activity. Predicted to be involved in several processes, including base-excision repair; oncogene-induced cell senescence; and regulation of DNA-templated transcription. Predicted to be located in nucleus and senescence-associated heterochromatin focus. Is expressed in several structures, including alimentary system; brain; respiratory system; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human HMGA1 (high mobility group AT-hook 1). [provided by Alliance of Genome Resources, Feb 2025]
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