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shRNA set against Mouse ERCC2 (NM_007949.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH286893

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Gene Information

Cat. No. SHH286893
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr ERCC2
Gene Name Ercc2 excision repair cross-complementing rodent repair deficiency, complementation group 2 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Ercc2 excision repair cross-complementing rodent repair deficiency, complementation group 2 [ Mus musculus ]
Gene Symbol Ercc2
Synonyms XPD; CXPD; Ercc-2; AA407812; AU020867; AW240756
Gene Description excision repair cross-complementing rodent repair deficiency, complementation group 2
GeneID 13871
Uni ProtID O08811
mRNA Refseq NM_007949.4
Protein Refseq NP_031975.2
Chromosome Location 7 A3; 7 4.0 cM
Function 4 iron, 4 sulfur cluster binding; 5-3 DNA helicase activity; ATP binding; ATP-dependent DNA helicase activity; ATP-dependent helicase activity; DNA binding; helicase activity; hydrolase activity; hydrolase activity, acting on acid anhydrides; hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; iron-sulfur cluster binding; metal ion binding; nucleic acid binding; nucleotide binding; protein C-terminus binding; protein N-terminus binding;
Pathway Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; DNA Repair, organism-specific biosystem; Dual incision reaction in GG-NER, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem; Formation of RNA Pol II elongation complex, organism-specific biosystem;
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