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shRNA set against Mouse CASP2 (NM_007610.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH254965

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Gene Information

Cat. No. SHH254965
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CASP2
Gene Name Casp2 caspase 2 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Casp2 caspase 2 [ Mus musculus ]
Gene Symbol Casp2
Synonyms ICH-1; Nedd2; Caspase-2
Gene Description caspase 2
GeneID 12366
Uni ProtID P29594
mRNA Refseq NM_007610.1
Protein Refseq NP_031636.1
Chromosome Location 6 B2.1; 6 20.5 cM
Function cysteine-type endopeptidase activity; cysteine-type peptidase activity; hydrolase activity; peptidase activity; peptidase activity; protein binding; protein domain specific binding;
Pathway Apoptosis, organism-specific biosystem; Apoptosis Modulation by HSP70, organism-specific biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; NADE modulates death signalling, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signalling by NGF, organism-specific biosystem;
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