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shRNA set against Human WFS1 (NM_006005.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH446944

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Gene Information

Cat. No. SHH446944
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr WFS1
Gene Name WFS1 Wolfram syndrome 1 (wolframin) [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name WFS1 Wolfram syndrome 1 (wolframin) [ Homo sapiens ]
Gene Symbol WFS1
Synonyms WFS1; Wolfram syndrome 1 (wolframin); DFNA6, DFNA14, DFNA38; wolframin; DIDMOAD; WFS; WFRS; WFSL; FLJ51211;
Gene ID 7466
Uni Prot ID O76024
m RNA Refseq BC030130
Chromosome Location 4p16.1
Function ATPase binding; activating transcription factor binding; transporter activity; ubiquitin protein ligase binding;
Pathway Activation of Chaperone Genes by XBP1(S), organism-specific biosystem; Activation of Chaperones by IRE1alpha, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem; Unfolded Protein Response, organism-specific biosystem;
MIM 606201
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