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shRNA set against Human Sh2b2 (NM_020979.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH406468

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Gene Information

Cat. No. SHH406468
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr Sh2b2
Gene Name SH2B2 SH2B adaptor protein 2 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name SH2B2 SH2B adaptor protein 2 [ Homo sapiens ]
Gene Symbol SH2B2
Synonyms APS
Gene ID 10603
Uni Prot ID O14492
m RNA Refseq NM_020979.3
Protein Refseq NP_066189.3
Chromosome Location 7q22
Function JAK pathway signal transduction adaptor activity; SH3/SH2 adaptor activity; phospholipid binding; signal transducer activity;
Pathway B Cell Receptor Signaling Pathway, organism-specific biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Hemostasis, organism-specific biosystem; IL-5 Signaling Pathway, organism-specific biosystem; Insulin Pathway, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; Insulin signaling pathway, organism-specific biosystem;
MIM 605300
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