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shRNA set against Human PMVK (NM_006556.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH378524

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Gene Information

Cat. No. SHH378524
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr PMVK
Gene Name PMVK phosphomevalonate kinase [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name PMVK phosphomevalonate kinase [ Homo sapiens ]
Gene Symbol PMVK
Synonyms PMK; PMKA; PMKASE; HUMPMKI
Gene Description phosphomevalonate kinase
GeneID 10654
Uni ProtID Q15126
mRNA Refseq NM_006556.3
Protein Refseq NP_006547.1
Chromosome Location 1q22
Function ATP binding; phosphomevalonate kinase activity;
Pathway Activation of Gene Expression by SREBP (SREBF), organism-specific biosystem; C5 isoprenoid biosynthesis, mevalonate pathway, organism-specific biosystem; C5 isoprenoid biosynthesis, mevalonate pathway, conserved biosystem; Cholesterol Biosynthesis, organism-specific biosystem; Cholesterol biosynthesis, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem;
MIM 607622
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