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shRNA set against Human NEK2 (NM_002497.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH351228

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Gene Information

Cat. No. SHH351228
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr NEK2
Gene Name NEK2 NIMA (never in mitosis gene a)-related kinase 2 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name NEK2 NIMA (never in mitosis gene a)-related kinase 2 [ Homo sapiens ]
Gene Symbol NEK2
Synonyms NEK2; NIMA (never in mitosis gene a)-related kinase 2; serine/threonine-protein kinase Nek2; HsPK 21; NEK2A; NLK1; nimA-like protein kinase 1; nimA-related protein kinase 2; HsPK21;
GeneID 4751
Uni ProtID P51955
mRNA Refseq BC065932
Chromosome Location 1q32-q42
Function ATP binding; metal ion binding; nucleotide binding; protein binding; protein kinase activity; protein phosphatase binding; protein serine/threonine kinase activity;
Pathway Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; FOXM1 transcription factor network, organism-specific biosystem; G2/M Transition, organism-specific biosystem; Loss of Nlp from mitotic centrosomes, organism-specific biosystem; Loss of proteins required for interphase microtubule organization from the centrosome, organism-specific biosystem;
MIM 604043
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