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shRNA set against Human NCF1 (NM_000265.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH349933

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Gene Information

Cat. No. SHH349933
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr NCF1
Gene Name NCF1 neutrophil cytosolic factor 1 [ Homo sapiens ]
Species Human
Resistance Hygromycin
Selection Hygromycin
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name NCF1 neutrophil cytosolic factor 1 [ Homo sapiens ]
Gene Symbol NCF1
Synonyms NCF1A; NOXO2; p47phox; SH3PXD1A
Gene Description neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1)
Gene ID 653361
Uni Prot ID P14598
m RNA Refseq NM_000265.4
Protein Refseq NP_000256.3
Chromosome Location 7q11.23
Function GTP binding; GTPase activity; SH3 domain binding; electron carrier activity; phosphatidylinositol binding; protein binding; superoxide-generating NADPH oxidase activity;
Pathway Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; Leishmaniasis, organism-specific biosystem; Leishmaniasis, conserved biosystem; Leukocyte transendothelial migration, organism-specific biosystem;
MIM 608512
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