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shRNA set against Human MED12 (NM_005120.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH339859

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Gene Information

Cat. No. SHH339859
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr MED12
Gene Name MED12 mediator complex subunit 12 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name MED12 mediator complex subunit 12 [ Homo sapiens ]
Gene Symbol MED12
Synonyms OKS; FGS1; HOPA; OPA1; ARC240; CAGH45; MED12S; TNRC11; TRAP230
Gene Description mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae)
GeneID 9968
Uni ProtID Q93074
mRNA Refseq NM_005120.2
Protein Refseq NP_005111.2
Chromosome Location Xq13
Function RNA polymerase II transcription cofactor activity; beta-catenin binding; ligand-dependent nuclear receptor transcription coactivator activity; protein C-terminus binding; protein domain specific binding; receptor activity; thyroid hormone receptor binding; transcription coactivator activity; transcription cofactor activity; vitamin D receptor binding;
Pathway Developmental Biology, organism-specific biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; PPARA Activates Gene Expression, organism-specific biosystem;
MIM 300188
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