shRNA set against Human HLCS (NM_000411.6)

Name: shRNA set against Human HLCS (NM_000411.6)
SKU: SHH313125
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH313125

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Product Information

Gene Information

Cat. No.	SHH313125
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	HLCS
Gene Name	HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) [ Homo sapiens ]
Gene Symbol	HLCS
Synonyms	HLCS; holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase); holocarboxylase synthetase (biotin (proprionyl Coenzyme A carboxylase (ATP hydrolysing)) ligase) , holocarboxylase synthetase (biotin [proprionyl Coenzyme A carboxylase (ATP hydrolysing)] ligase); biotin--protein ligase; HCS; biotin apo-protein ligase; biotin--[acetyl-CoA-carboxylase] ligase; biotin--[methylcrotonoyl-CoA-carboxylase] ligase; biotin--[methylmalonyl-CoA-carboxytransferase] ligase; holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase);
GeneID	3141
Uni ProtID	P50747
mRNA Refseq	BC060787
Chromosome Location	21q22.1
Function	ATP binding; biotin binding; biotin-[acetyl-CoA-carboxylase] ligase activity; biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity; biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity; biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity; biotin-protein ligase activity; biotin-protein ligase activity; enzyme binding; ligase activity; nucleotide binding; protein homodimerization activity;
Pathway	Biotin metabolism, organism-specific biosystem; Biotin metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; biotin-carboxyl carrier protein assembly, organism-specific biosystem;
MIM	609018

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