shRNA set against Human EXOSC1 (NM_016046.3)

Name: shRNA set against Human EXOSC1 (NM_016046.3)
SKU: SHH288077
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH288077

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Product Information

Gene Information

Cat. No.	SHH288077
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	EXOSC1
Gene Name	EXOSC1 exosome component 1 [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	EXOSC1 exosome component 1 [ Homo sapiens ]
Gene Symbol	EXOSC1
Synonyms	EXOSC1; exosome component 1; exosome complex component CSL4; CGI 108; CSL4; CSL4 exosomal core protein homolog (yeast); Csl4p; hCsl4p; p13; SKI4; Ski4p; exosomal core protein CSL4; 3-5 exoribonuclease CSL4 homolog; CSL4 exosomal core protein homolog; homolog of yeast exosomal core protein CSL4; CGI-108; RP11-452K12.9;
GeneID	51013
Uni ProtID	Q9Y3B2
mRNA Refseq	BC022067
Chromosome Location	10q24
Function	RNA binding; NOT exoribonuclease activity; protein binding;
Pathway	Activation of Genes by ATF4, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by KSRP, organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem;
MIM	606493

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