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shRNA set against Human CASP4 (NM_001225.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH254985

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Gene Information

Cat. No. SHH254985
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr CASP4
Gene Name CASP4 caspase 4, apoptosis-related cysteine peptidase [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name CASP4 caspase 4, apoptosis-related cysteine peptidase [ Homo sapiens ]
Gene Symbol CASP4
Synonyms TX; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II
Gene Description caspase 4, apoptosis-related cysteine peptidase
Gene ID 837
Uni Prot ID P49662
m RNA Refseq NM_033306.2
Protein Refseq NP_150649.1
Chromosome Location 11q22.2-q22.3
Function cysteine-type endopeptidase activity;
Pathway Apoptosis, organism-specific biosystem; Caspase cascade in apoptosis, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; NOD1/2 Signaling Pathway, organism-specific biosystem; Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways, organism-specific biosystem;
MIM 602664
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