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PRV-CMV-EGFP

For research use only. Not intended for any clinical use.

Cat. No. :   VNTP-1

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Virus Particles Information

Cat. No. VNTP-1
Description Pseudorabies virus (PRV) Bartha-derived replication-competent retrograde polysynaptic neuronal tracer expressing enhanced green fluorescent protein (EGFP) under the CMV promoter. PRV Bartha exhibits selective retrograde transneuronal transport and infects neurons via nectin receptor-mediated fusion. After injection at peripheral or central terminals, the virus is taken up, replicates in infected neurons, and its progeny virions cross synapses retrogradely across multiple synaptic levels, labeling the entire input network with bright green fluorescence. PRV has a wide host range and infects all mammals except higher primates.
Product Type Pseudorabies virus
Reporter EGFP (Enhanced Green Fluorescent Protein)
Synaptic Transmission Multi-synaptic (Polysynaptic)
TKStatus Full-length TK (replication-competent)
Applications
  1. Retrograde multi-synaptic (polysynaptic) neuronal tracing to map brain-wide multi-level input networks to a specific region
  2. Tracing from peripheral organs to the central nervous system
  3. Studying neural network reorganization during development, disease, and injury
  4. Characterizing afferent circuits to peripheral targets and brain regions
  5. Identifying polysynaptic inputs to defined brain areas.
Size Custom
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Dry ice
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