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Human JAK1 KO Cell Line-Hela

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-RT2844

Target Gene :   JAK1 Host Cell :   HeLa

Size :   >1x106 cells/vial Validation :   Sequencing

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Cell Line Information

Cell Culture Information

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Gene Information

Cat. No. CSC-RT2844
Description This cell is a stable cell line with a homozygous knockout of human JAK1 using CRISPR/Cas9.
Target Gene JAK1
Host Cell HeLa
Host Cell Species Homo sapiens (Human)
Size 1 vial (>10^6 cell/vial)
Validation Sequencing
Storage Liquid Nitrogen
Shipping Dry ice package
Revival Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name JAK1 Janus kinase 1 [ Homo sapiens ]
Gene Symbol JAK1
Synonyms JTK3; JAK1A; JAK1B
Gene Description Janus kinase 1 (a protein tyrosine kinase)
GeneID 3716
Uni ProtID P23458
mRNA Refseq NM_002227.2
Protein Refseq NP_002218.2
Chromosome Location 1p32.3-p31.3
Function ATP binding; growth hormone receptor binding; non-membrane spanning protein tyrosine kinase activity; protein binding; protein tyrosine kinase activity; protein tyrosine kinase activity;
Pathway Antiviral mechanism by IFN-stimulated genes, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Epstein-Barr virus infection, organism-specific biosystem; Epstein-Barr virus infection, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem;
MIM 147795
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