Panoply™ Human ZFP36 Knockdown Stable Cell Line

Name: Panoply™ Human ZFP36 Knockdown Stable Cell Line
SKU: CSC-DC017792
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC017792

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC017792
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ZFP36
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ZFP36 zinc finger protein 36, C3H type, homolog (mouse) [ Homo sapiens ]
Gene Symbol	ZFP36
Synonyms	ZFP36; zinc finger protein 36, C3H type, homolog (mouse); zinc finger protein, C3H type, 36 homolog (mouse); tristetraprolin; G0S24; NUP475; RNF162A; TIS11; TTP; zfp-36; tristetraproline; zinc finger protein 36 homolog; G0/G1 switch regulatory protein 24; zinc finger protein, C3H type, 36 homolog; growth factor-inducible nuclear protein NUP475; GOS24;
Gene ID	7538
Uni Prot ID	P26651
m RNA Refseq	BC009693
Chromosome Location	19q13.1
Function	14-3-3 protein binding; AU-rich element binding; AU-rich element binding; C-C chemokine binding; DNA binding; mRNA binding; metal ion binding; protein bindin
Pathway	Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; ErbB1 downstream signaling, organism-specific biosystem; Gene Expression, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Regulation of mRNA Stability by Proteins that Bind AU-rich Elements, organism-specific biosystem;
MIM	190700

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