Panoply™ Human ZBP1 Knockdown Stable Cell Line

Name: Panoply™ Human ZBP1 Knockdown Stable Cell Line
SKU: CSC-DC017665
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC017665

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC017665
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ZBP1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ZBP1 Z-DNA binding protein 1 [ Homo sapiens ]
Gene Symbol	ZBP1
Synonyms	ZBP1; Z-DNA binding protein 1; C20orf183, chromosome 20 open reading frame 183; Z-DNA-binding protein 1; DAI; dJ718J7.3; DLM 1; DLM1; DNA dependent activator of IRFs; DNA-dependent activator of IRFs; DNA-dependent activator of IFN-regulatory factors; tumor stroma and activated macrophage protein DLM-1; DNA-dependent activator of interferon regulatory factors; DLM-1; C20orf183;
GeneID	81030
Uni ProtID	Q9H171
mRNA Refseq	BC028218
Chromosome Location	20q13.31
Function	DNA binding; RNA binding; double-stranded RNA adenosine deaminase activity; left-handed Z-DNA binding;
Pathway	Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Cytosolic sensors of pathogen-associated DNA, organism-specific biosystem; DAI mediated induction of type I IFNs, organism-specific biosystem; IRF3 mediated activation of type 1 IFN, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem;
MIM	606750

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