Panoply™ Human YWHAB Knockdown Stable Cell Line

Name: Panoply™ Human YWHAB Knockdown Stable Cell Line
SKU: CSC-DC017643
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC017643

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC017643
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	YWHAB
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide [ Homo sapiens ]
Gene Symbol	YWHAB
Synonyms	HS1; GW128; YWHAA; KCIP-1
Gene Description	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
Gene ID	7529
Uni Prot ID	P31946
m RNA Refseq	NM_003404.3
Protein Refseq	NP_003395.1
Chromosome Location	20q13.1
Function	enzyme binding; histone deacetylase binding; phosphoprotein binding; phosphoserine binding; protein C-terminus binding; protein binding; protein domain specific binding; transcription corepressor activity;
Pathway	ARMS-mediated activation, organism-specific biosystem; Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Alpha6-Beta4 Integrin Signaling Pathway, organism-specific biosystem; Apoptosis, organism-specific biosystem; Axon guidance, organism-specific biosystem;
MIM	601289

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