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Panoply™ Human UBR2 Knockdown Stable Cell Line

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-DC017004

Host Cell :   HEK293 (Hela and other cell types are also available) Validation :   Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No. CSC-DC017004
Description Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene UBR2
Host Cell HEK293 (Hela and other cell types are also available)
Host Cell Species Homo sapiens (Human)
Applications

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size >1 × 106 cells / vial
Stability Validated for at least 10 passages
Validation Real-Time RCR
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid Nitrogen
Shipping Dry Ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name UBR2 ubiquitin protein ligase E3 component n-recognin 2 [ Homo sapiens ]
Gene Symbol UBR2
Synonyms UBR2; ubiquitin protein ligase E3 component n-recognin 2; C6orf133, chromosome 6 open reading frame 133; E3 ubiquitin-protein ligase UBR2; bA49A4.1; dJ392M17.3; KIAA0349; ubiquitin-protein ligase E3-alpha-2; ubiquitin-protein ligase E3-alpha-II; C6orf133; dJ242G1.1; RP3-392M17.3; FLJ36357; MGC71112; DKFZp686C08114;
Gene ID 23304
Uni Prot ID Q8IWV8
m RNA Refseq BC064512
Chromosome Location 6p21.1
Function leucine binding; ligase activity; metal ion binding; ubiquitin-protein ligase activity; zinc ion binding;
Pathway Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem;
MIM 609134
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