Panoply™ Human TYRP1 Knockdown Stable Cell Line

Name: Panoply™ Human TYRP1 Knockdown Stable Cell Line
SKU: CSC-DC016916
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC016916

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC016916
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	TYRP1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TYRP1 tyrosinase-related protein 1 [ Homo sapiens ]
Gene Symbol	TYRP1
Synonyms	TRP; CAS2; CATB; GP75; OCA3; TYRP; SHEP11; b-PROTEIN
Gene ID	7306
Uni Prot ID	P17643
m RNA Refseq	NM_000550.2
Protein Refseq	NP_000541.1
Chromosome Location	9p23
Function	copper ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen; protein binding; protein heterodimerization activity; protein homodimerization activity;
Pathway	Direct p53 effectors, organism-specific biosystem; Melanogenesis, organism-specific biosystem; Melanogenesis, conserved biosystem; Tyrosine metabolism, organism-specific biosystem; Tyrosine metabolism, conserved biosystem; ethanol degradation IV, organism-specific biosystem; superoxide radicals degradation, organism-specific biosystem;
MIM	115501

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