Panoply™ Human TYR Knockdown Stable Cell Line

Name: Panoply™ Human TYR Knockdown Stable Cell Line
SKU: CSC-DC016913
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC016913

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-DC016913
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	TYR
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TYR tyrosinase (oculocutaneous albinism IA) [ Homo sapiens ]
Gene Symbol	TYR
Synonyms	CMM8; OCA1A; OCAIA; SHEP3
Gene Description	tyrosinase (oculocutaneous albinism IA)
Gene ID	7299
Uni Prot ID	P14679
m RNA Refseq	NM_000372.4
Protein Refseq	NP_000363.1
Chromosome Location	11q14-q21
Function	copper ion binding; monophenol monooxygenase activity; protein binding; protein heterodimerization activity; protein homodimerization activity;
Pathway	(S)-reticuline biosynthesis II, conserved biosystem; Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline, organism-specific biosystem; Catecholamine biosynthesis, tyrosine => dopamine =>
MIM	606933

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