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Panoply™ Human TSC2 Knockdown Stable Cell Line

Cat.No.
CSC-DC016700
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
TSC2
Synonyms
LAM; TSC4
Gene Description
tuberous sclerosis 2
Gene ID
UniProt ID
P49815
mRNA Refseq
Protein Refseq
Chromosome Location
16p13.3
Function
14-3-3 protein binding; GTPase activator activity; phosphatase binding; protein binding; protein heterodimerization activity; protein homodimerization activity;
Pathway
AKT phosphorylates targets in the cytosol, organism-specific biosystem; AMPK signaling, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Constitutive PI3K/AKT Signaling in Cancer, organism-specific biosystem; DAP12 interactions, organism-specific biosystem; DAP12 signaling, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem;
MIM

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