Panoply™ Human TRIM25 Knockdown Stable Cell Line

Name: Panoply™ Human TRIM25 Knockdown Stable Cell Line
SKU: CSC-DC016577
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC016577

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC016577
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	TRIM25
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TRIM25 tripartite motif containing 25 [ Homo sapiens ]
Gene Symbol	TRIM25
Synonyms	EFP; Z147; RNF147; ZNF147
Gene Description	tripartite motif-containing 25
Gene ID	7706
Uni Prot ID	Q14258
m RNA Refseq	NM_005082.4
Protein Refseq	NP_005073.2
Chromosome Location	17q23.2
Function	protein binding; sequence-specific DNA binding transcription factor activity; ubiquitin-protein ligase activity; zinc ion binding;
Pathway	Antiviral mechanism by IFN-stimulated genes, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; ISG15 antiviral mechanism, organism-specific biosystem; Immune System, organism-specific biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem; Innate Immune System, organism-specific biosystem;
MIM	600453

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