Panoply™ Human TOP3A Knockdown Stable Cell Line

Name: Panoply™ Human TOP3A Knockdown Stable Cell Line
SKU: CSC-DC016436
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC016436

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

Inquire for Price

Cell Line Information

Safety and Packaging

Gene Information

Cat. No.	CSC-DC016436
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	TOP3A
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TOP3A topoisomerase (DNA) III alpha [ Homo sapiens ]
Gene Symbol	TOP3A
Synonyms	TOP3
Gene Description	topoisomerase (DNA) III alpha
Gene ID	7156
Uni Prot ID	Q13472
m RNA Refseq	NM_004618.3
Protein Refseq	NP_004609.1
Chromosome Location	17p12-p11.2
Function	ATP binding; DNA binding; DNA topoisomerase activity; DNA topoisomerase type I activity; protein binding; zinc ion binding;
Pathway	Blooms syndrome complex, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem; Meiosis, organism-specific biosystem; Meiotic Recombination, organism-specific biosystem;
MIM	601243

Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *