Panoply™ Human TLE2 Knockdown Stable Cell Line

Name: Panoply™ Human TLE2 Knockdown Stable Cell Line
SKU: CSC-DC015989
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC015989

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC015989
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	TLE2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TLE2 transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila) [ Homo sapiens ]
Gene Symbol	TLE2
Synonyms	TLE2; transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila); transducin like enhancer of split 2, homolog of Drosophila E(sp1); transducin-like enhancer protein 2; enhancer of split groucho 2; ESG; ESG2; FLJ41188; GRG2; enhancer of split groucho-like protein 2; transducin-like enhancer of split 2, homolog of Drosophila E(sp1);
Gene ID	7089
Uni Prot ID	Q04725
m RNA Refseq	BC017364
Chromosome Location	19p13.3
Function	protein binding; transcription corepressor activity;
Pathway	NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Regulation of Wnt-mediated beta catenin signaling and target gene transcription, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem; Signaling by NOTCH1, organism-specific biosystem;
MIM	601041

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