Panoply™ Human TICAM2 Knockdown Stable Cell Line

Name: Panoply™ Human TICAM2 Knockdown Stable Cell Line
SKU: CSC-DC015941
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC015941

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC015941
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	TICAM2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TICAM2 toll-like receptor adaptor molecule 2 [ Homo sapiens ]
Gene Symbol	TICAM2
Synonyms	TICAM2; toll-like receptor adaptor molecule 2; TIR domain-containing adapter molecule 2; TICAM 2; TIRP; TRAM; cytoplasmic adaptor; TRIF-related adaptor molecule; NF-kappa-B-activating protein 502; toll-like receptor adaptor protein 3; putative NF-kappa-B-activating protein 502; toll/interleukin-1 receptor (TIR) domain-containing adapter protein; TIRAP3; TICAM-2; MGC129876; MGC129877;
Gene ID	353376
Uni Prot ID	Q86XR7
m RNA Refseq	BC109266
Chromosome Location	5q15-q32
Function	signal transducer activity;
Pathway	Activated TLR4 signalling, organism-specific biosystem; Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, organism-specific biosystem; IKK complex recruitment mediated by RIP1, organism-specific biosystem; IL1-mediated signaling events, organism-specific biosystem; IRAK2 mediated activation of TAK1 complex, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem;
MIM	608321

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