Panoply™ Human TFAP2B Knockdown Stable Cell Line

Name: Panoply™ Human TFAP2B Knockdown Stable Cell Line
SKU: CSC-DC015833
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC015833

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC015833
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	TFAP2B
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta) [ Homo sapiens ]
Gene Symbol	TFAP2B
Synonyms	AP-2B; AP2-B
Gene Description	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
Gene ID	7021
Uni Prot ID	A8K557
m RNA Refseq	NM_003221.3
Protein Refseq	NP_003212.2
Chromosome Location	6p12
Function	DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding; RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity; RNA polymerase II transcription coactivator activity; RNA polymerase II transcription corepressor activity; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; enhancer sequence-specific DNA binding; protein binding; protein dimerization activity; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding; sequence-specific DNA binding RNA polymerase II transcription factor activity; sequence-specific DNA binding transcription factor activity; transcription coactivator activity; transcription corepressor activity;
Pathway	Neural Crest Differentiation, organism-specific biosystem;
MIM	601601

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