Panoply™ Human TAB3 Knockdown Stable Cell Line

Name: Panoply™ Human TAB3 Knockdown Stable Cell Line
SKU: CSC-DC015525
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC015525

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC015525
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	TAB3
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 [ Homo sapiens ]
Gene Symbol	MAP3K7IP3
Synonyms	NAP1; MAP3K7IP3
Gene Description	mitogen-activated protein kinase kinase kinase 7 interacting protein 3
GeneID	257397
Uni ProtID	Q8N5C8
mRNA Refseq	NM_152787.3
Protein Refseq	NP_690000.2
Chromosome Location	Xp21.2
Function	protein binding; zinc ion binding;
Pathway	Activated TLR4 signalling, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; IRAK2 mediated activation of TAK1 complex, organism-specific biosystem; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; Interleukin-1 signaling, organism-specific biosystem;
MIM	300480

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