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Panoply™ Human STAT3 Knockdown Stable Cell Line

Cat.No.
CSC-DC015282
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
STAT3
Synonyms
APRF; HIES
Gene Description
signal transducer and activator of transcription 3 (acute-phase response factor)
Gene ID
UniProt ID
P40763
mRNA Refseq
Protein Refseq
Chromosome Location
17q21.31
Function
CCR5 chemokine receptor binding; DNA binding; calcium ion binding; glucocorticoid receptor binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; protein binding; protein dimerization activity; protein kinase binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; signal transducer activity; transcription factor binding; transcription regulatory region DNA binding;
Pathway
Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem;
MIM

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