Panoply™ Human SPR Knockdown Stable Cell Line

Name: Panoply™ Human SPR Knockdown Stable Cell Line
SKU: CSC-DC015088
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC015088

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC015088
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	SPR
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) [ Homo sapiens ]
Gene Symbol	SPR
Synonyms	SDR38C1
GeneID	6697
Uni ProtID	P35270
mRNA Refseq	NM_003124.4
Protein Refseq	NP_003115.1
Chromosome Location	2p14-p12
Function	NADP binding; aldo-keto reductase (NADP) activity; sepiapterin reductase activity; sepiapterin reductase activity;
Pathway	Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; Metabolism, organism-specific biosystem; Metabolism of nitric oxide, organism-specific biosystem; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation, organism-specific biosystem; eNOS activation and regulation, organism-specific biosystem; tetrahydrobiopterin biosynthesis I, organism-specific biosystem;
MIM	182125

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