Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
HEK293 (Hela and other cell types are also available)
Negative for bacteria, yeast, fungi and mycoplasma.
DNA binding; HMG box domain binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding; RNA polymerase II repressing transcription factor binding; bHLH transcription factor binding; double-stranded DNA binding; enhancer binding; histone acetyltransferase binding; histone deacetylase binding; protein C-terminus binding; protein binding; protein homodimerization activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; transcription regulatory region DNA binding; zinc ion binding;