Panoply™ Human SOX9 Knockdown Stable Cell Line

Name: Panoply™ Human SOX9 Knockdown Stable Cell Line
SKU: CSC-DC014925
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC014925

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC014925
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	SOX9
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	SOX9 SRY (sex determining region Y)-box 9 [ Homo sapiens ]
Gene Symbol	SOX9
Synonyms	CMD1; SRA1; CMPD1
GeneID	6662
Uni ProtID	P48436
mRNA Refseq	NM_000346.3
Protein Refseq	NP_000337.1
Chromosome Location	17q23
Function	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; beta-catenin binding; chromatin binding; core promoter sequence-specific DNA binding; enhancer binding; enhancer sequence-specific DNA binding; protein binding; protein kinase A catalytic subunit binding; protein kinase activity; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity;
Pathway	Endochondral Ossification, organism-specific biosystem; Neural Crest Differentiation, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem;
MIM	608160

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