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Panoply™ Human SOS2 Knockdown Stable Cell Line

Cat.No.
CSC-DC014900
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
SOS2
Synonyms
SOS2; son of sevenless homolog 2 (Drosophila); son of sevenless (Drosophilia) homolog 2; son of sevenless homolog 2; SOS-2; guanine nucleotide exchange factor; guanine nucleotide releasing factor; FLJ25596;
Gene ID
UniProt ID
Q07890
mRNA Refseq
BC117261
Chromosome Location
14q21
Function
DNA binding; Rho guanyl-nucleotide exchange factor activity; guanyl-nucleotide exchange factor activity; protein binding;
Pathway
Activation of Rac, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; Axon guidance, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem;
MIM

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