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Panoply™ Human SOS1 Knockdown Stable Cell Line

Cat.No.
CSC-DC014899
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
SOS1
Synonyms
GF1; HGF; NS4; GGF1; GINGF
Gene Description
son of sevenless homolog 1 (Drosophila)
Gene ID
UniProt ID
Q07889
mRNA Refseq
Protein Refseq
Chromosome Location
2p21
Function
DNA binding; Ras guanyl-nucleotide exchange factor activity; Ras guanyl-nucleotide exchange factor activity; Rho GTPase activator activity; Rho guanyl-nucleotide exchange factor activity; phospholipid binding; protein binding; protein heterodimerization activity;
Pathway
Activation of Rac, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; Antigen Activates B Cell Receptor Leading to Generation of Second Messengers, organism-specific biosystem;
MIM

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