Panoply™ Human SMPD3 Knockdown Stable Cell Line

Name: Panoply™ Human SMPD3 Knockdown Stable Cell Line
SKU: CSC-DC014770
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC014770

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC014770
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	SMPD3
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) [ Homo sapiens ]
Gene Symbol	SMPD3
Synonyms	SMPD3; sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II); sphingomyelin phosphodiesterase 3; NSMASE2; nSMase-2; neutral sphingomyelinase 2; neutral sphingomyelinase II; FLJ22593; MGC138443;
Gene ID	55512
Uni Prot ID	Q9NY59
m RNA Refseq	BC112238
Chromosome Location	16q22.1
Function	hydrolase activity; metal ion binding; sphingomyelin phosphodiesterase activity;
Pathway	Ceramide signaling pathway, organism-specific biosystem; Glycosphingolipid metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem;
MIM	605777

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