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Panoply™ Human SMG6 Knockdown Stable Cell Line

Cat.No.
CSC-DC014752
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
SMG6
Synonyms
EST1A; SMG-6; C17orf31; hSMG5/7a
Gene Description
Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)
Gene ID
UniProt ID
Q86US8
mRNA Refseq
Protein Refseq
Chromosome Location
17p13.3
Function
endoribonuclease activity; endoribonuclease activity; endoribonuclease activity; metal ion binding; protein binding; telomeric DNA binding;
Pathway
Gene Expression, organism-specific biosystem; Nonsense Mediated Decay Enhanced by the Exon Junction Complex, organism-specific biosystem; Nonsense-Mediated Decay, organism-specific biosystem; Regulation of Telomerase, organism-specific biosystem; mRNA surveillance pathway, organism-specific biosystem; mRNA surveillance pathway, conserved biosystem;
MIM

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