Panoply™ Human SLC8A1 Knockdown Stable Cell Line

Name: Panoply™ Human SLC8A1 Knockdown Stable Cell Line
SKU: CSC-DC014653
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC014653

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC014653
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	SLC8A1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 [ Homo sapiens ]
Gene Symbol	SLC8A1
Synonyms	NCX1
Gene Description	solute carrier family 8 (sodium/calcium exchanger), member 1
GeneID	6546
Uni ProtID	P32418
mRNA Refseq	NM_021097.2
Protein Refseq	NP_066920.1
Chromosome Location	2p23-p22
Function	ankyrin binding; ankyrin binding; calcium:sodium antiporter activity; calmodulin binding; cytoskeletal protein binding; heat shock protein binding; ion channel binding; metal ion binding;
Pathway	Arrhythmogenic right ventricular cardiomyopathy, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Cardiac muscle contraction, organism-specific biosystem;
MIM	182305

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