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Panoply™ Human SKI Knockdown Stable Cell Line

Cat.No.
CSC-DC014287
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
SKI
Synonyms
SGS; SKV
Gene Description
v-ski sarcoma viral oncogene homolog (avian)
Gene ID
UniProt ID
P12755
mRNA Refseq
Protein Refseq
Chromosome Location
1p36.33
Function
SMAD binding; chromatin binding; histone deacetylase inhibitor activity; nucleotide binding; protein binding; protein domain specific binding; protein kinase binding; repressing transcription factor binding; transcription corepressor activity; transcription corepressor activity; ubiquitin protein ligase binding; zinc ion binding;
Pathway
BMP Signalling Pathway, organism-specific biosystem; BMP receptor signaling, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; Downregulation of SMAD2/3:SMAD4 transcriptional activity, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Hedgehog Signaling Pathway, organism-specific biosystem;
MIM

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