Panoply™ Human RNF135 Knockdown Stable Cell Line

Name: Panoply™ Human RNF135 Knockdown Stable Cell Line
SKU: CSC-DC013383
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC013383

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC013383
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	RNF135
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	RNF135 ring finger protein 135 [ Homo sapiens ]
Gene Symbol	RNF135
Synonyms	L13; MMFD; REUL; Riplet
Gene Description	ring finger protein 135
Gene ID	84282
Uni Prot ID	Q8IUD6
m RNA Refseq	NM_197939.1
Protein Refseq	NP_922921.1
Chromosome Location	17q11.2
Pathway	Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10, organism-specific biosystem; Negative regulators of RIG-I/MDA5 signaling, organism-specific biosystem; RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways, organism-specific biosystem; TRAF3-dependent IRF activation pathway, organism-specific biosystem; TRAF6 mediated IRF7 activation, organism-specific biosystem;
MIM	611358

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