Panoply™ Human RFC1 Knockdown Stable Cell Line

Name: Panoply™ Human RFC1 Knockdown Stable Cell Line
SKU: CSC-DC013185
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC013185

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC013185
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	RFC1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	RFC1 replication factor C (activator 1) 1, 145kDa [ Homo sapiens ]
Gene Symbol	RFC1
Synonyms	RFC1; replication factor C (activator 1) 1, 145kDa; replication factor C (activator 1) 1 (145kD); replication factor C subunit 1; A1; MHCBFB; PO GA; RFC140; A1 140 kDa subunit; RF-C 140 kDa subunit; activator 1 subunit 1; replication factor C1; MHC binding factor, beta; DNA-binding protein PO-GA; activator 1 large subunit; activator 1 140 kDa subunit; replication factor C large subunit; replication factor C 140 kDa subunit; RFC; PO-GA; RECC1; MGC51786;
GeneID	5981
Uni ProtID	P35251
mRNA Refseq	BC035297
Chromosome Location	4p14-p13
Function	ATP binding; DNA clamp loader activity; enzyme activator activity; nucleos
Pathway	BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Repair, organism-specific biosystem; DNA Replication, organism-specific biosystem; DNA Replication, organism-specific biosystem;
MIM	102579

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