Panoply™ Human RAPGEF2 Knockdown Stable Cell Line

Name: Panoply™ Human RAPGEF2 Knockdown Stable Cell Line
SKU: CSC-DC012968
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC012968

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC012968
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	RAPGEF2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 [ Homo sapiens ]
Gene Symbol	RAPGEF2
Synonyms	RAPGEF2; Rap guanine nucleotide exchange factor (GEF) 2; PDZ domain containing guanine nucleotide exchange factor (GEF) 1 , PDZGEF1; rap guanine nucleotide exchange factor 2; DKFZP586O1422; KIAA0313; PDZ GEF1; RA GEF; Rap GEP; RA(Ras/Rap1A-associating)-GEF; neural RAP guanine nucleotide exchange protein; PDZ domain-containing guanine nucleotide exchange factor 1; PDZ domain containing guanine nucleotide exchange factor (GEF) 1; RA-GEF; NRAPGEP; PDZGEF1; Rap-GEP; CNrasGEF; PDZ-GEF1; nRap GEP;
Gene ID	9693
Uni Prot ID	Q9Y4G8
m RNA Refseq	BC117321
Chromosome Location	4q32.1
Function	Rap GTPase activator activity; Rap guanyl-nucleotide exchange factor activity; calcium ion binding; diacylglycerol binding; guanyl-nucleotide exchange factor activity; signal transducer activity;
Pathway	MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem;
MIM	609530

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