Panoply™ Human PPP1R12A Knockdown Stable Cell Line

Name: Panoply™ Human PPP1R12A Knockdown Stable Cell Line
SKU: CSC-DC012231
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC012231

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC012231
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	PPP1R12A
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	PPP1R12A protein phosphatase 1, regulatory subunit 12A [ Homo sapiens ]
Gene Symbol	PPP1R12A
Synonyms	PPP1R12A; protein phosphatase 1, regulatory subunit 12A; MYPT1, protein phosphatase 1, regulatory (inhibitor) subunit 12A; protein phosphatase 1 regulatory subunit 12A; M130; MBS; myosin binding subunit; myosin phosphatase targeting subunit 1; myosin phosphatase, target subunit 1; myosin phosphatase-targeting subunit 1; protein phosphatase myosin-binding subunit; protein phosphatase 1, regulatory (inhibitor) subunit 12A; MYPT1; MGC133042;
GeneID	4659
Uni ProtID	O14974
mRNA Refseq	BC111752
Chromosome Location	12q15-q21
Function	14-3-3 protein binding; phosphatase regulator activity; phosphatase regulator activity;
Pathway	Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; Long-term potentiation, organism-specific biosystem; Long-term potentiation, conserved biosystem; PLK1 signaling events, organism-specific biosystem; Regulation of Actin Cytoskeleton, organism-specific biosystem;
MIM	602021

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