Panoply™ Human POU1F1 Knockdown Stable Cell Line

Name: Panoply™ Human POU1F1 Knockdown Stable Cell Line
SKU: CSC-DC012144
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC012144

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC012144
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	POU1F1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	POU1F1 POU class 1 homeobox 1 [ Homo sapiens ]
Gene Symbol	POU1F1
Synonyms	PIT1; CPHD1; GHF-1; Pit-1; POU1F1a
Gene ID	5449
Uni Prot ID	P28069
m RNA Refseq	NM_000306.2
Protein Refseq	NP_000297.1
Chromosome Location	3p11
Function	RNA polymerase II activating transcription factor binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II transcription coactivator activity; chromatin binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;
Pathway	Glucocorticoid receptor regulatory network, organism-specific biosystem;
MIM	173110

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