Panoply™ Human POLR2J Knockdown Stable Cell Line

Name: Panoply™ Human POLR2J Knockdown Stable Cell Line
SKU: CSC-DC012098
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC012098

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC012098
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	POLR2J
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa [ Homo sapiens ]
Gene Symbol	POLR2J
Synonyms	RPB11; RPB11A; RPB11m; hRPB14; POLR2J1
Gene Description	polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
Gene ID	5439
Uni Prot ID	P52435
m RNA Refseq	NM_006234.4
Protein Refseq	NP_006225.1
Chromosome Location	7q22.1
Function	DNA binding; DNA-directed RNA polymerase activity; LRR domain binding; protein binding; contributes_to protein kinase activity;
Pathway	Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; DNA Repair, organism-specific biosystem; Disease, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Epstein-Barr virus infection, organism-specific biosystem; Epstein-Barr virus infection, conserved biosystem; Eukaryotic Transcription Initiation, organism-specific biosystem;
MIM	604150

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