Panoply™ Human POLR2H Knockdown Stable Cell Line

Name: Panoply™ Human POLR2H Knockdown Stable Cell Line
SKU: CSC-DC012096
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC012096

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC012096
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	POLR2H
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	POLR2H polymerase (RNA) II (DNA directed) polypeptide H [ Homo sapiens ]
Gene Symbol	POLR2H
Synonyms	RPB8; RPB17; RPABC3; hsRPB8
Gene Description	polymerase (RNA) II (DNA directed) polypeptide H
Gene ID	5437
Uni Prot ID	P52434
m RNA Refseq	NM_006232.2
Protein Refseq	NP_006223.2
Chromosome Location	3q28
Function	DNA-directed RNA polymerase activity; contributes_to protein kinase activity; zinc ion binding;
Pathway	Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; DNA Repair, organism-specific biosystem; Disease, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Epstein-Barr virus infection, organism-specific biosystem;
MIM	606023

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