Panoply™ Human POLR2D Knockdown Stable Cell Line

Name: Panoply™ Human POLR2D Knockdown Stable Cell Line
SKU: CSC-DC012092
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC012092

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC012092
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	POLR2D
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	POLR2D polymerase (RNA) II (DNA directed) polypeptide D [ Homo sapiens ]
Gene Symbol	POLR2D
Synonyms	RBP4; RPB16; HSRBP4; HSRPB4
Gene Description	polymerase (RNA) II (DNA directed) polypeptide D
Gene ID	5433
Uni Prot ID	O15514
m RNA Refseq	NM_004805.3
Protein Refseq	NP_004796.1
Chromosome Location	2q21
Function	DNA-directed RNA polymerase activity; nucleotide binding; contributes_to protein kinase activity;
Pathway	Abortive elongation of HIV-1 transcript in the absence of Tat, organism-specific biosystem; DNA Repair, organism-specific biosystem; Disease, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Epstein-Barr virus infection, organism-specific biosystem; Epstein-Barr virus infection, conserved biosystem; Formation of HIV-1 elongation complex containing HIV-1 Tat, organism-specific biosystem;
MIM	606017

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