Panoply™ Human POLG2 Knockdown Stable Cell Line

Name: Panoply™ Human POLG2 Knockdown Stable Cell Line
SKU: CSC-DC012076
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC012076

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC012076
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	POLG2
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	POLG2 polymerase (DNA directed), gamma 2, accessory subunit [ Homo sapiens ]
Gene Symbol	POLG2
Synonyms	POLG2; polymerase (DNA directed), gamma 2, accessory subunit; DNA polymerase subunit gamma-2, mitochondrial; HP55; MTPOLB; p55; mitochondrial DNA polymerase subunit gamma-2; DNA polymerase gamma accessory 55 kDa subunit; mitochondrial DNA polymerase accessory subunit; mitochondrial DNA polymerase, accessory subunit; POLB; PEOA4; POLGB; POLG-BETA;
Gene ID	11232
Uni Prot ID	Q9UHN1
m RNA Refseq	BC009194
Chromosome Location	17q
Function	ATP binding; DNA binding; DNA-directed DNA polymerase activity; glycine-tRNA ligase activity; identical protein binding; nucleotide binding; nucleotidyltransferase activity; protein binding; single-stranded DNA binding; transferase activity;
Pathway	DNA polymerase gamma complex, organism-specific biosystem; Metabolic pathways, organism-specific biosystem;
MIM	604983

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