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Panoply™ Human POLE Knockdown Stable Cell Line

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Cat.No.
CSC-DC012071
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Gene
POLE
Gene Species
Human
Host Cell
HEK293 (Hela and other cell types are also available)
Growth Properties
Adherent
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Size
2 × 10^6 cells / vial
Storage
Liquid Nitrogen
Ship
Dry Ice
Gene Information
Official Symbol
POLE
Synonyms
POLE1
GeneID
mRNA Refseq
Protein Refseq
MIM
UniProt ID
Q07864
Chromosome Location
12q24.3
Pathway
Activation of the pre-replicative complex, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Repair, organism-specific biosystem;
Function
4 iron, 4 sulfur cluster binding; DNA binding; DNA-directed DNA polymerase activity; chromatin binding; nucleotide binding; zinc ion binding;

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