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Panoply™ Human POLA1 Knockdown Stable Cell Line

Cat.No.
CSC-DC012062
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
POLA1
Synonyms
POLA; p180
Gene ID
UniProt ID
P09884
mRNA Refseq
Protein Refseq
Chromosome Location
Xp22.1-p21.3
Function
3-5 exonuclease activity; 4 iron, 4 sulfur cluster binding; DNA binding; DNA binding; contributes_to DNA primase activity; DNA-directed DNA polymerase activity; DNA-directed DNA polymerase activity; chromatin binding; double-stranded DNA binding; metal ion binding; nucleoside binding; nucleotide binding; protein binding; protein heterodimerization activity; purine nucleotide binding; pyrimidine nucleotide binding;
Pathway
Activation of the pre-replicative complex, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Replication, organism-specific biosystem; DNA Replication, organism-specific biosystem; DNA Replication Pre-Initiation, organism-specific biosystem;
MIM

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